Role of Ionizing Radiation in Neurodegenerative Diseases

Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, where...

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Autores principales: Sharma, Neel K., Sharma, Rupali, Mathur, Deepali, Sharad, Shashwat, Minhas, Gillipsie, Bhatia, Kulsajan, Anand, Akshay, Ghosh, Sanchita P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963202/
https://www.ncbi.nlm.nih.gov/pubmed/29867445
http://dx.doi.org/10.3389/fnagi.2018.00134
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author Sharma, Neel K.
Sharma, Rupali
Mathur, Deepali
Sharad, Shashwat
Minhas, Gillipsie
Bhatia, Kulsajan
Anand, Akshay
Ghosh, Sanchita P.
author_facet Sharma, Neel K.
Sharma, Rupali
Mathur, Deepali
Sharad, Shashwat
Minhas, Gillipsie
Bhatia, Kulsajan
Anand, Akshay
Ghosh, Sanchita P.
author_sort Sharma, Neel K.
collection PubMed
description Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, whereas chronic effects may persist for a number of years. Radiation can increase many circulatory, age related and neurodegenerative diseases. Neurodegenerative diseases occur a long time after exposure to radiation, as demonstrated in atomic bomb survivors, and are still controversial. This review discuss the role of IR in neurodegenerative diseases and proposes an association between neurodegenerative diseases and exposure to IR.
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spelling pubmed-59632022018-06-04 Role of Ionizing Radiation in Neurodegenerative Diseases Sharma, Neel K. Sharma, Rupali Mathur, Deepali Sharad, Shashwat Minhas, Gillipsie Bhatia, Kulsajan Anand, Akshay Ghosh, Sanchita P. Front Aging Neurosci Neuroscience Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness. At high-dose exposures acute radiation sickness occurs, whereas chronic effects may persist for a number of years. Radiation can increase many circulatory, age related and neurodegenerative diseases. Neurodegenerative diseases occur a long time after exposure to radiation, as demonstrated in atomic bomb survivors, and are still controversial. This review discuss the role of IR in neurodegenerative diseases and proposes an association between neurodegenerative diseases and exposure to IR. Frontiers Media S.A. 2018-05-14 /pmc/articles/PMC5963202/ /pubmed/29867445 http://dx.doi.org/10.3389/fnagi.2018.00134 Text en At least a portion of this work is authored by Neel K. Sharma, Rupali Sharma, Shashwat Sharad and Sanchita P. Ghosh on behalf of the U.S. Government and, as regards Drs. Sharma, Sharma, Sharad, Ghosh and the US government, is not subject to copyright protection in the United States. Foreign and other copyrights may apply. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Sharma, Neel K.
Sharma, Rupali
Mathur, Deepali
Sharad, Shashwat
Minhas, Gillipsie
Bhatia, Kulsajan
Anand, Akshay
Ghosh, Sanchita P.
Role of Ionizing Radiation in Neurodegenerative Diseases
title Role of Ionizing Radiation in Neurodegenerative Diseases
title_full Role of Ionizing Radiation in Neurodegenerative Diseases
title_fullStr Role of Ionizing Radiation in Neurodegenerative Diseases
title_full_unstemmed Role of Ionizing Radiation in Neurodegenerative Diseases
title_short Role of Ionizing Radiation in Neurodegenerative Diseases
title_sort role of ionizing radiation in neurodegenerative diseases
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963202/
https://www.ncbi.nlm.nih.gov/pubmed/29867445
http://dx.doi.org/10.3389/fnagi.2018.00134
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