TOPK Promotes Microglia/Macrophage Polarization towards M2 Phenotype via Inhibition of HDAC1 and HDAC2 Activity after Transient Cerebral Ischemia

T-LAK-cell-originated protein kinase (TOPK) is a newly identified member of the mitogen-activated protein kinase family. Our previous study has showed that TOPK has neuroprotective effects against cerebral ischemia-reperfusion injury. Here, we investigated the involvement of TOPK in microglia/ macro...

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Detalles Bibliográficos
Autores principales: Han, Ziping, Zhao, Haiping, Tao, Zhen, Wang, Rongliang, Fan, Zhibin, Luo, Yumin, Luo, Yinghao, Ji, Xunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963345/
https://www.ncbi.nlm.nih.gov/pubmed/29896413
http://dx.doi.org/10.14336/AD.2017.0328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963345/
https://www.ncbi.nlm.nih.gov/pubmed/29896413
http://dx.doi.org/10.14336/AD.2017.0328

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