An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify g...

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Detalles Bibliográficos
Autores principales: Syn, Genevieve, Blackwell, Jenefer M, Jamieson, Sarra E, Francis, Richard W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963570/
https://www.ncbi.nlm.nih.gov/pubmed/29846382
http://dx.doi.org/10.1590/0074-02760170471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963570/
https://www.ncbi.nlm.nih.gov/pubmed/29846382
http://dx.doi.org/10.1590/0074-02760170471

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