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Polymorphisms in the promoter region of the CRBN gene as a predictive factor for the first-line CTD therapy in multiple myeloma patients

Cereblon is a primary molecular target for immunomodulatory drugs. The aim of this study was to evaluate the influence of selected clinical and molecular factors including single nucleotide polymorphisms (SNPs) in CRBN gene on the efficacy of first line CTD (cyclophosphamide, thalidomide, dexamethas...

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Detalles Bibliográficos
Autores principales:	Szudy-Szczyrek, Aneta, Mlak, Radosław, Szczyrek, Michał, Chocholska, Sylwia, Sompor, Jacek, Nogalski, Adam, Małecka-Massalska, Teresa, Hus, Marek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963627/ https://www.ncbi.nlm.nih.gov/pubmed/29844872 http://dx.doi.org/10.18632/oncotarget.25307

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