Evaluation of Hepatoprotective Effect of Acantholimon Gilliati Eerial Part Methanolic Extract

The aerial parts of Acantholimon gilliati was extracted by n-hexane, dichloromethane and methanol. Methanolic extract tested for hepatoprotective effects on formaldehyde liver injury in mice. The maximum effect that the methanolic extract showed protective effect on this experiment against formaldeh...

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Detalles Bibliográficos
Autores principales: Gazor, Rouhollah, Asgari, Mehrdad, Pasdaran, Ardalan, Mohammadghasemi, Fahimeh, Nasiri, Ebrahim, Atrkar Roushan, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963654/
https://www.ncbi.nlm.nih.gov/pubmed/29844784
Descripción
Sumario:The aerial parts of Acantholimon gilliati was extracted by n-hexane, dichloromethane and methanol. Methanolic extract tested for hepatoprotective effects on formaldehyde liver injury in mice. The maximum effect that the methanolic extract showed protective effect on this experiment against formaldehyde observed in 5 and 10 mg. Also other concentrations of this extract showed positive effect compared to toxicant on morphology and biochemical factors of the liver. Results showed that the methanolic extract of the A. gilliati has a protective include functional and enzymatic stablingeffect on liver.

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