Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells

The Hes1 dimer inhibitor, agalloside (2), which can accelerate the differentiation of neural stem cells is described. Six natural products, including one new natural product, which bind to Hes1 were rapidly isolated by a developed “target protein oriented natural products isolation” (TPO-NAPI) metho...

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Detalles Bibliográficos
Autores principales: Arai, Midori A., Ishikawa, Naoki, Tanaka, Mitsuha, Uemura, Kenji, Sugimitsu, Noriko, Suganami, Akiko, Tamura, Yutaka, Koyano, Takashi, Kowithayakorn, Thaworn, Ishibashi, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963671/
https://www.ncbi.nlm.nih.gov/pubmed/29899896
http://dx.doi.org/10.1039/c5sc03540f

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