Cargando…

Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis

BACKGROUND: The aim of this study was to assess the efficacy and safety of acupuncture therapy for patients with hypertension. MATERIAL/METHODS: We searched PubMed, Embase, the Cochrane Library, the Chinese Biomedical Literature Database, the Chinese National Knowledge Infrastructure, and the Wan-fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hao, Shen, Fei-er, Tan, Xiao-dong, Jiang, Wen-bo, Gu, Yi-huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963739/
https://www.ncbi.nlm.nih.gov/pubmed/29735972
http://dx.doi.org/10.12659/MSM.909995
_version_ 1783325068104826880
author Chen, Hao
Shen, Fei-er
Tan, Xiao-dong
Jiang, Wen-bo
Gu, Yi-huang
author_facet Chen, Hao
Shen, Fei-er
Tan, Xiao-dong
Jiang, Wen-bo
Gu, Yi-huang
author_sort Chen, Hao
collection PubMed
description BACKGROUND: The aim of this study was to assess the efficacy and safety of acupuncture therapy for patients with hypertension. MATERIAL/METHODS: We searched PubMed, Embase, the Cochrane Library, the Chinese Biomedical Literature Database, the Chinese National Knowledge Infrastructure, and the Wan-fang Data Database from inception through 29 April 2017. Randomized controlled trials investigating acupuncture therapy for hypertension were included. Review Manager 5.3 software was used for the data analysis. RESULTS: A total of 30 RCTs involving 2107 patients were included. The overall methodological quality of the included studies was low. Pooled results demonstrate that acupuncture plus anti-hypertensive drugs is better than anti-hypertensive drugs alone at reducing systolic and diastolic blood pressure (SBP and DBP). The same result was observed for pooled data from experiments that compared acupuncture plus medication to sham acupuncture plus medication at reducing SBP and DBP. However, studies reveal that using acupuncture alone or anti-hypertensive drugs alone do not differ in the effect on lowering blood pressure. Similarly, acupuncture alone also did not differ from sham acupuncture alone, and electroacupuncture versus anti-hypertensive drugs was not significantly different at reducing SBP and DBP. CONCLUSIONS: Our systematic review indicates there is inadequate high quality evidence that acupuncture therapy is useful in treating hypertension, as the exact effect and safety of acupuncture therapy for hypertension is still unclear. Therefore, research with larger sample sizes and higher-quality RCTs is still needed.
format Online
Article
Text
id pubmed-5963739
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher International Scientific Literature, Inc.
record_format MEDLINE/PubMed
spelling pubmed-59637392018-05-30 Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis Chen, Hao Shen, Fei-er Tan, Xiao-dong Jiang, Wen-bo Gu, Yi-huang Med Sci Monit Meta-Analysis BACKGROUND: The aim of this study was to assess the efficacy and safety of acupuncture therapy for patients with hypertension. MATERIAL/METHODS: We searched PubMed, Embase, the Cochrane Library, the Chinese Biomedical Literature Database, the Chinese National Knowledge Infrastructure, and the Wan-fang Data Database from inception through 29 April 2017. Randomized controlled trials investigating acupuncture therapy for hypertension were included. Review Manager 5.3 software was used for the data analysis. RESULTS: A total of 30 RCTs involving 2107 patients were included. The overall methodological quality of the included studies was low. Pooled results demonstrate that acupuncture plus anti-hypertensive drugs is better than anti-hypertensive drugs alone at reducing systolic and diastolic blood pressure (SBP and DBP). The same result was observed for pooled data from experiments that compared acupuncture plus medication to sham acupuncture plus medication at reducing SBP and DBP. However, studies reveal that using acupuncture alone or anti-hypertensive drugs alone do not differ in the effect on lowering blood pressure. Similarly, acupuncture alone also did not differ from sham acupuncture alone, and electroacupuncture versus anti-hypertensive drugs was not significantly different at reducing SBP and DBP. CONCLUSIONS: Our systematic review indicates there is inadequate high quality evidence that acupuncture therapy is useful in treating hypertension, as the exact effect and safety of acupuncture therapy for hypertension is still unclear. Therefore, research with larger sample sizes and higher-quality RCTs is still needed. International Scientific Literature, Inc. 2018-05-08 /pmc/articles/PMC5963739/ /pubmed/29735972 http://dx.doi.org/10.12659/MSM.909995 Text en © Med Sci Monit, 2018 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Meta-Analysis
Chen, Hao
Shen, Fei-er
Tan, Xiao-dong
Jiang, Wen-bo
Gu, Yi-huang
Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis
title Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis
title_full Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis
title_fullStr Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis
title_full_unstemmed Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis
title_short Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis
title_sort efficacy and safety of acupuncture for essential hypertension: a meta-analysis
topic Meta-Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963739/
https://www.ncbi.nlm.nih.gov/pubmed/29735972
http://dx.doi.org/10.12659/MSM.909995
work_keys_str_mv AT chenhao efficacyandsafetyofacupunctureforessentialhypertensionametaanalysis
AT shenfeier efficacyandsafetyofacupunctureforessentialhypertensionametaanalysis
AT tanxiaodong efficacyandsafetyofacupunctureforessentialhypertensionametaanalysis
AT jiangwenbo efficacyandsafetyofacupunctureforessentialhypertensionametaanalysis
AT guyihuang efficacyandsafetyofacupunctureforessentialhypertensionametaanalysis