Angiogenic and pleiotropic effects of VEGF165 and HGF combined gene therapy in a rat model of myocardial infarction

Since development of plasmid gene therapy for therapeutic angiogenesis by J. Isner this approach was an attractive option for ischemic diseases affecting large cohorts of patients. However, first placebo-controlled clinical trials showed its limited efficacy questioning further advance to practice....

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Detalles Bibliográficos
Autores principales: Makarevich, Pavel I., Dergilev, Konstantin V., Tsokolaeva, Zoya I., Boldyreva, Maria A., Shevchenko, Evgeniy K., Gluhanyuk, Evgeny V., Gallinger, Julia O., Menshikov, Mikhail Yu., Parfyonova, Yelena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963747/
https://www.ncbi.nlm.nih.gov/pubmed/29787588
http://dx.doi.org/10.1371/journal.pone.0197566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963747/
https://www.ncbi.nlm.nih.gov/pubmed/29787588
http://dx.doi.org/10.1371/journal.pone.0197566

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