RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA(A) receptors involved in volume regulation

To identify coding and non-coding suppressor genes of anchorage-independent proliferation by efficient loss-of-function screening, we have developed a method for enzymatic production of low complexity shRNA libraries from subtracted transcriptomes. We produced and screened two LEGO (Low-complexity b...

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Detalles Bibliográficos
Autores principales: Wielders, Camiel L. C., van Nierop, Pim, Vormer, Tinke L., Foijer, Floris, Verheij, Joanne, Lodder, Johannes C., Andersen, Jesper B., Mansvelder, Huibert D., te Riele, Hein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963783/
https://www.ncbi.nlm.nih.gov/pubmed/29787571
http://dx.doi.org/10.1371/journal.pone.0196979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963783/
https://www.ncbi.nlm.nih.gov/pubmed/29787571
http://dx.doi.org/10.1371/journal.pone.0196979

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