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Prediction from Creatinine Clearance of Thrombocytopenia and Recommended Dose in Patients Receiving (Glycolato‐O, O′)‐diammine Platinum (II) (NSC 375101D)

Thrombocytopenia is the most serious dose‐limiting toxicity of (glycolato‐O, O′)‐diammine platinum (II) (254‐S; NSC 375101D), one of the new platinum analogues. A total of 38 patients treated with 100 mg of 254‐S per m(2) in a clinical phase II study were retrospectively analyzed to determine the fa...

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Detalles Bibliográficos
Autores principales: Sasaki, Yasutsuna, Fukuda, Masaaki, Morita, Masashige, Shinkai, Tetsu, Eguchi, Kenji, Tamura, Tomohide, Ohe, Yuichiro, Yamada, Kohzo, Kojima, Akira, Nakagawa, Kazuhiko, Ohmori, Toru, Saijo, Nagahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963895/
https://www.ncbi.nlm.nih.gov/pubmed/2110134
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02548.x