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Analysis of Clonal Evolution in a Tumor Consisting of pSV2neo‐transfected Mouse Fibrosarcoma Clones

The process of clonal evolution was analyzed in a line of methylcholanthrene‐induced mouse fibrosarcomas. The tumor cells were transfected with pSV2neo gene and 22 clones were randomly isolated. Genetically tagged clones were mixed and inoculated into syngeneic mice. Southern blot analysis revealed...

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Detalles Bibliográficos
Autores principales: Enoki, Yoshitaka, Niwa, Ohtsura, Yokoro, Kenjiro, Toge, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963897/
https://www.ncbi.nlm.nih.gov/pubmed/2110131
http://dx.doi.org/10.1111/j.1349-7006.1990.tb02540.x