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Analysis of Clonal Evolution in a Tumor Consisting of pSV2neo‐transfected Mouse Fibrosarcoma Clones
The process of clonal evolution was analyzed in a line of methylcholanthrene‐induced mouse fibrosarcomas. The tumor cells were transfected with pSV2neo gene and 22 clones were randomly isolated. Genetically tagged clones were mixed and inoculated into syngeneic mice. Southern blot analysis revealed...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1990
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963897/ https://www.ncbi.nlm.nih.gov/pubmed/2110131 http://dx.doi.org/10.1111/j.1349-7006.1990.tb02540.x |