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SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program
The establishment and maintenance of pluripotency depend on precise coordination of gene expression. We establish serine-arginine-rich splicing factor 3 (SRSF3) as an essential regulator of RNAs encoding key components of the mouse pluripotency circuitry, SRSF3 ablation resulting in the loss of plur...
Autores principales: | Ratnadiwakara, Madara, Archer, Stuart K, Dent, Craig I, Ruiz De Los Mozos, Igor, Beilharz, Traude H, Knaupp, Anja S, Nefzger, Christian M, Polo, Jose M, Anko, Minna-Liisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963917/ https://www.ncbi.nlm.nih.gov/pubmed/29741478 http://dx.doi.org/10.7554/eLife.37419 |
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