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CD28 Costimulation of T Helper 1 Cells Enhances Cytokine Release In Vivo

Compared to naive T cells, differentiated T cells are thought to be less dependent on CD28 costimulation for full activation. To revisit the role of CD28 costimulation in mouse T cell recall responses, we adoptively transferred in vitro generated OT-II T helper (Th) 1 cells into C57BL/6 mice (Thy1.2...

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Detalles Bibliográficos
Autores principales:	Langenhorst, Daniela, Haack, Stephanie, Göb, Selina, Uri, Anna, Lühder, Fred, Vanhove, Bernard, Hünig, Thomas, Beyersdorf, Niklas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964139/ https://www.ncbi.nlm.nih.gov/pubmed/29868020 http://dx.doi.org/10.3389/fimmu.2018.01060

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