IL-37 isoform D downregulates pro-inflammatory cytokines expression in a Smad3-dependent manner

IL-37 is a new member of IL-1 family and possesses five different isoforms (named as IL-37 a–e). IL-37b has been demonstrated as a physiological suppressor of immune responses. However, the function of other isoforms remains unknown. Here, we show that IL-37d possesses anti-inflammatory roles both i...

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Detalles Bibliográficos
Autores principales: Zhao, Mingsheng, Li, Yulan, Guo, Chun, Wang, Liyang, Chu, Hongxia, Zhu, Faliang, Li, Yan, Wang, Xiaoyan, Wang, Qun, Zhao, Wei, Shi, Yongyu, Chen, WanJun, Zhang, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964144/
https://www.ncbi.nlm.nih.gov/pubmed/29789615
http://dx.doi.org/10.1038/s41419-018-0664-0

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