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L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast
The synthetic yeast genome constructed by the International Synthetic Yeast Sc2.0 consortium adds thousands of loxPsym recombination sites to all 16 redesigned chromosomes, allowing the shuffling of Sc2.0 chromosome parts by the Cre-loxP recombination system thereby enabling genome evolution experim...
Autores principales: | Hochrein, Lena, Mitchell, Leslie A., Schulz, Karina, Messerschmidt, Katrin, Mueller-Roeber, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964156/ https://www.ncbi.nlm.nih.gov/pubmed/29789561 http://dx.doi.org/10.1038/s41467-017-02208-6 |
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