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L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast

The synthetic yeast genome constructed by the International Synthetic Yeast Sc2.0 consortium adds thousands of loxPsym recombination sites to all 16 redesigned chromosomes, allowing the shuffling of Sc2.0 chromosome parts by the Cre-loxP recombination system thereby enabling genome evolution experim...

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Detalles Bibliográficos
Autores principales: Hochrein, Lena, Mitchell, Leslie A., Schulz, Karina, Messerschmidt, Katrin, Mueller-Roeber, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964156/
https://www.ncbi.nlm.nih.gov/pubmed/29789561
http://dx.doi.org/10.1038/s41467-017-02208-6

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