Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of these infections is a major hurdle of therapy because pulmonary NTM infections can persist in biofilms or as intrace...

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Detalles Bibliográficos
Autores principales: Zhang, Jimin, Leifer, Franziska, Rose, Sasha, Chun, Dung Yu, Thaisz, Jill, Herr, Tracey, Nashed, Mary, Joseph, Jayanthi, Perkins, Walter R., DiPetrillo, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964161/
https://www.ncbi.nlm.nih.gov/pubmed/29867826
http://dx.doi.org/10.3389/fmicb.2018.00915

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