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Ferroptosis-inducing agents compromise in vitro human islet viability and function

Human islet transplantation has been hampered by donor cell death associated with the islet preparation procedure before transplantation. Regulated necrosis pathways are biochemically and morphologically distinct from apoptosis. Recently, ferroptosis was identified as a non-apoptotic form of iron-de...

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Detalles Bibliográficos
Autores principales: Bruni, Antonio, Pepper, Andrew R., Pawlick, Rena L., Gala-Lopez, Boris, Gamble, Anissa F., Kin, Tatsuya, Seeberger, Karen, Korbutt, Gregory S., Bornstein, Stefan R., Linkermann, Andreas, Shapiro, A. M. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964226/
https://www.ncbi.nlm.nih.gov/pubmed/29789532
http://dx.doi.org/10.1038/s41419-018-0506-0