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TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14
The proteasome is a complex protease critical for protein quality control and cell regulation, and its dysfunction is associated with cancer and other diseases. However, the mechanisms that control proteasome activity in normal and malignant cells remain unclear. Here we report that TRIM11 enhances...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964324/ https://www.ncbi.nlm.nih.gov/pubmed/29581427 http://dx.doi.org/10.1038/s41467-018-03499-z |