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A haunted beast: Targeting STAT5B(N642H) in T-Cell Neoplasia
The somatic hot spot mutation STAT5B(N642H) was found in many T cell leukemia/lymphoma patients. We generated and analyzed a transgenic mouse model with hematopoietic STAT5B(N642H) expression that caused aggressive T-cell leukemia/lymphomas. Herein, we discuss the scientific merit of our model and i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964446/ https://www.ncbi.nlm.nih.gov/pubmed/29876519 http://dx.doi.org/10.1080/23723556.2018.1435181 |