Hemodynamic effects of HPMA copolymer based doxorubicin conjugate: A randomized controlled and comparative spectral study in conscious rats

Conjugation of Doxorubicin (DOX) to N-(2-hydroxypropyl) methylacrylamide copolymer (HPMA) has significantly reduced the DOX-associated cardiotoxicity. However, the reports on the impact of HPMA–DOX conjugates on the cardiovascular system such as blood pressure (BP) and heart rate (HR) were in restra...

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Detalles Bibliográficos
Autores principales: Cheah, Hoay Yan, Šarenac, Olivera, Arroyo, Juan J., Vasić, Marko, Lozić, Maja, Glumac, Sofija, Hoe, See Ziau, Hindmarch, Charles Colin Thomas, Murphy, David, Kiew, Lik Voon, Lee, Hong Boon, Vicent, María J., Chung, Lip Yong, Japundžić-Žigon, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964453/
https://www.ncbi.nlm.nih.gov/pubmed/28098511
http://dx.doi.org/10.1080/17435390.2017.1285071

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