Clostridium difficile Toxoid Vaccine Candidate Confers Broad Protection against a Range of Prevalent Circulating Strains in a Nonclinical Setting

Clostridium difficile infection (CDI) is a leading cause of nosocomial and antibiotic-associated diarrhea. A vaccine, based on formalin-inactivated toxins A and B purified from anaerobic cultures of C. difficile strain VPI 10463 (toxinotype 0), has been in development for the prevention of symptomat...

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Detalles Bibliográficos
Autores principales: Quemeneur, Laurence, Petiot, Nadine, Arnaud-Barbe, Nadège, Hessler, Catherine, Pietrobon, Patricia J., Londoño-Hayes, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Bacterial Infections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964523/
https://www.ncbi.nlm.nih.gov/pubmed/29632249
http://dx.doi.org/10.1128/IAI.00742-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964523/
https://www.ncbi.nlm.nih.gov/pubmed/29632249
http://dx.doi.org/10.1128/IAI.00742-17

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