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Clostridium difficile Toxoid Vaccine Candidate Confers Broad Protection against a Range of Prevalent Circulating Strains in a Nonclinical Setting
Clostridium difficile infection (CDI) is a leading cause of nosocomial and antibiotic-associated diarrhea. A vaccine, based on formalin-inactivated toxins A and B purified from anaerobic cultures of C. difficile strain VPI 10463 (toxinotype 0), has been in development for the prevention of symptomat...
Autores principales: | Quemeneur, Laurence, Petiot, Nadine, Arnaud-Barbe, Nadège, Hessler, Catherine, Pietrobon, Patricia J., Londoño-Hayes, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964523/ https://www.ncbi.nlm.nih.gov/pubmed/29632249 http://dx.doi.org/10.1128/IAI.00742-17 |
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