Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres

Background: Although thousands of clinical isolates of Plasmodium falciparum are being sequenced and analysed by short read technology, the data do not resolve the highly variable subtelomeric regions of the genomes that contain polymorphic gene families involved in immune evasion and pathogenesis....

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Detalles Bibliográficos
Autores principales: Otto, Thomas D., Böhme, Ulrike, Sanders, Mandy, Reid, Adam, Bruske, Ellen I., Duffy, Craig W., Bull, Pete C., Pearson, Richard D., Abdi, Abdirahman, Dimonte, Sandra, Stewart, Lindsay B., Campino, Susana, Kekre, Mihir, Hamilton, William L., Claessens, Antoine, Volkman, Sarah K., Ndiaye, Daouda, Amambua-Ngwa, Alfred, Diakite, Mahamadou, Fairhurst, Rick M., Conway, David J., Franck, Matthias, Newbold, Chris I., Berriman, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964635/
https://www.ncbi.nlm.nih.gov/pubmed/29862326
http://dx.doi.org/10.12688/wellcomeopenres.14571.1

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