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RNA sequencing analysis reveals quiescent microglia isolation methods from postnatal mouse brains and limitations of BV2 cells

BACKGROUND: Microglia play key roles in neuron–glia interaction, neuroinflammation, neural repair, and neurotoxicity. Currently, various microglial in vitro models including primary microglia derived from distinct isolation methods and immortalized microglial cell lines are extensively used. However...

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Detalles Bibliográficos
Autores principales: He, Yingbo, Yao, Xiang, Taylor, Natalie, Bai, Yuchen, Lovenberg, Timothy, Bhattacharya, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964710/
https://www.ncbi.nlm.nih.gov/pubmed/29788964
http://dx.doi.org/10.1186/s12974-018-1195-4

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