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RNA sequencing analysis reveals quiescent microglia isolation methods from postnatal mouse brains and limitations of BV2 cells
BACKGROUND: Microglia play key roles in neuron–glia interaction, neuroinflammation, neural repair, and neurotoxicity. Currently, various microglial in vitro models including primary microglia derived from distinct isolation methods and immortalized microglial cell lines are extensively used. However...
Autores principales: | He, Yingbo, Yao, Xiang, Taylor, Natalie, Bai, Yuchen, Lovenberg, Timothy, Bhattacharya, Anindya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964710/ https://www.ncbi.nlm.nih.gov/pubmed/29788964 http://dx.doi.org/10.1186/s12974-018-1195-4 |
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