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Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants

Acetylcholine receptor antagonists have been shown to improve outcome in patients with severe acute respiratory distress syndrome. However, it is incompletely understood how these agents improve outcome. In the current editorial, we discuss the mechanisms of action of acetylcholine receptor antagoni...

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Detalles Bibliográficos
Autores principales: Jansen, Diana, de Vries, Heder, Heunks, Leo M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964732/
https://www.ncbi.nlm.nih.gov/pubmed/29788993
http://dx.doi.org/10.1186/s13054-018-1979-z
Descripción
Sumario:Acetylcholine receptor antagonists have been shown to improve outcome in patients with severe acute respiratory distress syndrome. However, it is incompletely understood how these agents improve outcome. In the current editorial, we discuss the mechanisms of action of acetylcholine receptor antagonists beyond neuromuscular blockade.