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Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen–antibody interactions
We report the chemical synthesis of the first photo-activatable protein antigen that can be used to study antigen–antibody interaction mediated responses in B cells. This strategy facilitated fine tuning of the caged protein antigen to optimize its bioactivity and photochemical properties. One optim...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965250/ https://www.ncbi.nlm.nih.gov/pubmed/29899912 http://dx.doi.org/10.1039/c5sc03404c |