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Increased burn healing time is associated with higher Vancouver Scar Scale score

[Image: see text] Increased burn wound healing time has been shown to influence abnormal scarring. This study hypothesised that scar severity increases commensurate to the increase in time to healing (TTH) of the wound. Wound healing and scar data from burn patients treated by the Burn Service of We...

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Autores principales: Finlay, Vidya, Burrows, Sally, Burmaz, Maddison, Yawary, Hussna, Lee, Johanna, Edgar, Dale W., Wood, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965328/
https://www.ncbi.nlm.nih.gov/pubmed/29799543
http://dx.doi.org/10.1177/2059513117696324
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author Finlay, Vidya
Burrows, Sally
Burmaz, Maddison
Yawary, Hussna
Lee, Johanna
Edgar, Dale W.
Wood, Fiona M.
author_facet Finlay, Vidya
Burrows, Sally
Burmaz, Maddison
Yawary, Hussna
Lee, Johanna
Edgar, Dale W.
Wood, Fiona M.
author_sort Finlay, Vidya
collection PubMed
description [Image: see text] Increased burn wound healing time has been shown to influence abnormal scarring. This study hypothesised that scar severity increases commensurate to the increase in time to healing (TTH) of the wound. Wound healing and scar data from burn patients treated by the Burn Service of Western Australia at Royal Perth Hospital were examined. The relationship between TTH and scar severity, as assessed by the modified Vancouver Scar Scale (mVSS), was modelled using regression analysis. Interaction terms evaluated the effect of surgery and total body surface area – burn (TBSA) on the main relationship. Maximum likelihood estimation was used to account for potential bias from missing independent variable data. The sample had a median age of 34 years, TTH of 24 days, TBSA of 3% and length of stay of five days, 70% were men and 71% had burn surgery. For each additional day of TTH, the mVSS score increased by 0.11 points (P ≤ 0.001) per day in the first 21 days and 0.02 points per day thereafter (P = 0.004). The relationship remained stable in spite of TBSA or surgical intervention. Investigation of the effect of missing data revealed the primary model underestimated the strength of the association. An increase in TTH within 21 days of injury is associated with an increase in mVSS or reduced scar quality. The results confirm that efforts should be directed toward healing burn wounds as early as possible.
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spelling pubmed-59653282018-05-24 Increased burn healing time is associated with higher Vancouver Scar Scale score Finlay, Vidya Burrows, Sally Burmaz, Maddison Yawary, Hussna Lee, Johanna Edgar, Dale W. Wood, Fiona M. Scars Burn Heal Original Article [Image: see text] Increased burn wound healing time has been shown to influence abnormal scarring. This study hypothesised that scar severity increases commensurate to the increase in time to healing (TTH) of the wound. Wound healing and scar data from burn patients treated by the Burn Service of Western Australia at Royal Perth Hospital were examined. The relationship between TTH and scar severity, as assessed by the modified Vancouver Scar Scale (mVSS), was modelled using regression analysis. Interaction terms evaluated the effect of surgery and total body surface area – burn (TBSA) on the main relationship. Maximum likelihood estimation was used to account for potential bias from missing independent variable data. The sample had a median age of 34 years, TTH of 24 days, TBSA of 3% and length of stay of five days, 70% were men and 71% had burn surgery. For each additional day of TTH, the mVSS score increased by 0.11 points (P ≤ 0.001) per day in the first 21 days and 0.02 points per day thereafter (P = 0.004). The relationship remained stable in spite of TBSA or surgical intervention. Investigation of the effect of missing data revealed the primary model underestimated the strength of the association. An increase in TTH within 21 days of injury is associated with an increase in mVSS or reduced scar quality. The results confirm that efforts should be directed toward healing burn wounds as early as possible. SAGE Publications 2017-03-14 /pmc/articles/PMC5965328/ /pubmed/29799543 http://dx.doi.org/10.1177/2059513117696324 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Finlay, Vidya
Burrows, Sally
Burmaz, Maddison
Yawary, Hussna
Lee, Johanna
Edgar, Dale W.
Wood, Fiona M.
Increased burn healing time is associated with higher Vancouver Scar Scale score
title Increased burn healing time is associated with higher Vancouver Scar Scale score
title_full Increased burn healing time is associated with higher Vancouver Scar Scale score
title_fullStr Increased burn healing time is associated with higher Vancouver Scar Scale score
title_full_unstemmed Increased burn healing time is associated with higher Vancouver Scar Scale score
title_short Increased burn healing time is associated with higher Vancouver Scar Scale score
title_sort increased burn healing time is associated with higher vancouver scar scale score
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965328/
https://www.ncbi.nlm.nih.gov/pubmed/29799543
http://dx.doi.org/10.1177/2059513117696324
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