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Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1

Protein tyrosine phosphatases (PTPs) originating from eukaryotes or bacteria have been under intensive structural and biochemical investigation, whereas archaeal PTP proteins have not been investigated extensively; therefore, they are poorly understood. Here, we present the crystal structures of Tk-...

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Detalles Bibliográficos
Autores principales:	Yun, Hye-Yeoung, Lee, Jinhyuk, Kim, Hyunmin, Ryu, Hyojung, Shin, Ho-Chul, Oh, Byung-Ha, Ku, Bonsu, Kim, Seung Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965843/ https://www.ncbi.nlm.nih.gov/pubmed/29791483 http://dx.doi.org/10.1371/journal.pone.0197635

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