Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4(+)CD8(+) T cells in chronic Chagas disease patients

BACKGROUND: Chagas disease is caused by Trypanosoma cruzi. The persistence of the parasite is associated with the disease chronicity and the impairment of the cellular immune response. It has been reported that the CD4(+)CD8(+) T cell population expands in chronic Chagas disease patients. Few studie...

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Detalles Bibliográficos
Autores principales: Pérez-Antón, Elena, Egui, Adriana, Thomas, M. Carmen, Puerta, Concepción J., González, John Mario, Cuéllar, Adriana, Segovia, Manuel, López, Manuel Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965897/
https://www.ncbi.nlm.nih.gov/pubmed/29750791
http://dx.doi.org/10.1371/journal.pntd.0006480

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