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RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization
To survive diverse host environments, the human pathogen Streptococcus pneumoniae must prevent its self-produced, extremely high levels of peroxide from reacting with intracellular iron. However, the regulatory mechanism(s) by which the pneumococcus accomplishes this balance remains largely enigmati...
Autores principales: | Glanville, David G., Han, Lanlan, Maule, Andrew F., Woodacre, Alexandra, Thanki, Devsaagar, Abdullah, Iman Tajer, Morrissey, Julie A., Clarke, Thomas B., Yesilkaya, Hasan, Silvaggi, Nicholas R., Ulijasz, Andrew T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965902/ https://www.ncbi.nlm.nih.gov/pubmed/29750817 http://dx.doi.org/10.1371/journal.ppat.1007052 |
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