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Genetic variation in P2RX7 and pain tolerance

P2X7 is a nonselective cation channel activated by extracellular ATP. P2X7 activation contributes to the proinflammatory response to injury or bacterial invasion and mediates apoptosis. Recently, P2X7 function has been linked to chronic inflammatory and neuropathic pain. P2X7 may contribute to pain...

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Detalles Bibliográficos
Autores principales:	Kambur, Oleg, Kaunisto, Mari A., Winsvold, Bendik S., Wilsgaard, Tom, Stubhaug, Audun, Zwart, John A., Kalso, Eija, Nielsen, Christopher S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965926/ https://www.ncbi.nlm.nih.gov/pubmed/29470314 http://dx.doi.org/10.1097/j.pain.0000000000001188

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