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Frequently rearranged and overexpressed δ-catenin is responsible for low sensitivity of prostate cancer cells to androgen receptor and β-catenin antagonists
The mechanism of prostate cancer (PCa) progression towards the hormone refractory state remains poorly understood. Treatment options for such patients are limited and present a major clinical challenge. Previously, δ-catenin was reported to promote PCa cell growth in vitro and its increased level is...
Autores principales: | Zhang, Piyan, Schaefer-Klein, Janet, Cheville, John C., Vasmatzis, George, Kovtun, Irina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966253/ https://www.ncbi.nlm.nih.gov/pubmed/29849951 http://dx.doi.org/10.18632/oncotarget.25319 |
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