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Monitoring circulating tumor DNA revealed dynamic changes in KRAS status in patients with metastatic colorectal cancer

KRAS mutated circulating tumor DNA (MctDNA) can be monitored in the blood of patients with metastatic colorectal cancer (mCRC), but dynamic changes have not been determined. Four hundred and fifty-seven plasma samples were collected prospectively from 85 mCRC patients who underwent chemotherapy. Mct...

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Detalles Bibliográficos
Autores principales: Takayama, Yuji, Suzuki, Koichi, Muto, Yuta, Ichida, Kosuke, Fukui, Taro, Kakizawa, Nao, Ishikawa, Hideki, Watanabe, Fumiaki, Hasegawa, Fumi, Saito, Masaaki, Tsujinaka, Shingo, Futsuhara, Kazushige, Miyakura, Yasuyuki, Noda, Hiroshi, Konishi, Fumio, Rikiyama, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966256/
https://www.ncbi.nlm.nih.gov/pubmed/29849949
http://dx.doi.org/10.18632/oncotarget.25309