Investigation of C1-complex regions reveals new C1Q variants associated with protection from systemic lupus erythematosus, and affect its transcript abundance

Although rare variant C1Q deficiency was identified as causative risk for systemic lupus erythematosus (SLE), there are limited and inconsistent reports regarding the common polymorphisms of C1Q genes in SLE susceptibility. Furthermore, there are no reports concerning polymorphisms of C1S, C1R, and...

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Detalles Bibliográficos
Autores principales: Guo, Jianping, Gao, Yanyan, Wang, Yuxuan, Zou, Yundong, Du, Yan, Luo, Cainan, Shi, Yamei, Yang, Yue, Wu, Xinyu, Su, Yin, Wu, Lijun, Chen, Shi, Li, Zhanguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966390/
https://www.ncbi.nlm.nih.gov/pubmed/29795138
http://dx.doi.org/10.1038/s41598-018-26380-x

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