Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity

The development of nephrotoxicity largely limits the clinical use of chemotherapy. MiRNAs are able to target various genes and involved in the regulation of diverse cellular processes, including cell apoptosis and death. Our study showed that miR-181a expression was significantly increased after 5-f...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Yun, Zhang, Fei-Ran, Shang, Jin-Yan, Liu, Ying-Ying, Lv, Xiao-Fei, Yuan, Jia-Ni, Zhang, Ting-Ting, Li, Kai, Lin, Xiao-Chun, Liu, Xiu, Lei, Qingqing, Fu, Xiao-Dong, Zhou, Jia-Guo, Liang, Si-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966400/
https://www.ncbi.nlm.nih.gov/pubmed/29795190
http://dx.doi.org/10.1038/s41419-018-0677-8

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