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Docetaxel enhances lysosomal function through TFEB activation
Docetaxel is an effective and commonly used chemotherapeutic drug for cancer. Autophagy has been reported to be involved in the anticancer mechanism of docetaxel. However, the effect of docetaxel on lysosomal function remains elusive. In the present study, we first found that docetaxel treatment enh...
Autores principales: | Zhang, Jianbin, Wang, Jigang, Wong, Yin Kwan, Sun, Xin, Chen, Yun, Wang, Liming, Yang, Liu, Lu, Liqin, Shen, Han-Ming, Huang, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966422/ https://www.ncbi.nlm.nih.gov/pubmed/29795139 http://dx.doi.org/10.1038/s41419-018-0571-4 |
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