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Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments
Kinetochores are multi-protein complexes that power chromosome movements by tracking microtubules plus-ends in the mitotic spindle. Human kinetochores bind up to 20 microtubules, even though single microtubules can generate sufficient force to move chromosomes. Here, we show that high microtubule oc...
Autores principales: | Dudka, Damian, Noatynska, Anna, Smith, Chris A., Liaudet, Nicolas, McAinsh, Andrew D., Meraldi, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966435/ https://www.ncbi.nlm.nih.gov/pubmed/29795284 http://dx.doi.org/10.1038/s41467-018-04427-x |
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