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Cholinergic activity is essential for maintaining the anterograde transport of Choline Acetyltransferase in Drosophila
Cholinergic activity is essential for cognitive functions and neuronal homeostasis. Choline Acetyltransferase (ChAT), a soluble protein that synthesizes acetylcholine at the presynaptic compartment, is transported in bulk in the axons by the heterotrimeric Kinesin-2 motor. Axonal transport of solubl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966444/ https://www.ncbi.nlm.nih.gov/pubmed/29795337 http://dx.doi.org/10.1038/s41598-018-26176-z |