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Inhibition of LCMR1 and ATG12 by demethylation-activated miR-570-3p is involved in the anti-metastasis effects of metformin on human osteosarcoma

Epidemiological studies have demonstrated that metformin could mitigate the progression of several tumors. Although it has been proved that metformin could cause demethylation of DNA and lead to up-regulation of some encoding genes and non-coding RNAs, there is little data about the effects of metfo...

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Detalles Bibliográficos
Autores principales: Bao, Xing, Zhao, Libo, Guan, Hanfeng, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966512/
https://www.ncbi.nlm.nih.gov/pubmed/29795113
http://dx.doi.org/10.1038/s41419-018-0620-z

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