Cargando…

Inhibition of NF-κB Signaling Reduces the Stemness Characteristics of Lung Cancer Stem Cells

Cancer stem cells (CSCs) are a subpopulation of cancer cells that play a pivotal role in tumor development, invasion, metastasis, and recurrence. We and others have reported significant involvement of the NF-κB pathway in regulating CSCs of non-small cell lung cancer (NSCLC). In this study, we evalu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zakaria, Norashikin, Mohd Yusoff, Narazah, Zakaria, Zubaidah, Widera, Darius, Yahaya, Badrul Hisham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966538/ https://www.ncbi.nlm.nih.gov/pubmed/29868483 http://dx.doi.org/10.3389/fonc.2018.00166

Ejemplares similares

Targeting Lung Cancer Stem Cells: Research and Clinical Impacts
por: Zakaria, Norashikin, et al.
Publicado: (2017)

Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines
por: BAHARUDDIN, PUTERI, et al.
Publicado: (2016)

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells
por: Zakaria, Norashikin, et al.
Publicado: (2015)

Novel triple-positive markers identified in human non-small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics
por: Satar, Nazilah Abdul, et al.
Publicado: (2018)

Conditioned Medium of Human Menstrual Blood-Derived Endometrial Stem Cells Protects Against MPP(+)-Induced Cytotoxicity in vitro
por: Li, Han, et al.
Publicado: (2019)

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of chronic obstructive pulmonary disease (COPD)
por: Ridzuan, Noridzzaida, et al.
Publicado: (2021)

The Effects of Lentivirus-Mediated Gene Silencing of RARβ on the Stemness Capability of Non-Small Cell Lung Cancer
por: Abu Halim, Noor Hanis, et al.
Publicado: (2021)

Production and differential activity of recombinant human wild-type G6PD and G6PD(Viangchan)
por: Vengidasan, Lelamekala, et al.
Publicado: (2020)

Chromosomal 16p microdeletion in Rubinstein-Taybi syndrome detected by oligonucleotide-based array comparative genomic hybridization: a case report
por: Mohd Fadley, Md A, et al.
Publicado: (2012)

Uncovering the gray zone: mapping the global landscape of direct-to-consumer businesses offering interventions based on secretomes, extracellular vesicles, and exosomes
por: Asadpour, Atiyeh, et al.
Publicado: (2023)

Tumor necrosis factor alpha induced proliferation of adult neural stem cells is mediated via NF-κB
por: Widera, Darius, et al.
Publicado: (2007)

Synergistic Roles of Curcumin in Sensitising the Cisplatin Effect on a Cancer Stem Cell-Like Population Derived from Non-Small Cell Lung Cancer Cell Lines
por: Abdul Satar, Nazilah, et al.
Publicado: (2021)

Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
por: Widera, Darius, et al.
Publicado: (2006)

The Rabbit as a Model for Studying Lung Disease and Stem Cell Therapy
por: Kamaruzaman, Nurfatin Asyikhin, et al.
Publicado: (2013)

Menstrual blood-derived endometrial stem cell, a unique and promising alternative in the stem cell-based therapy for chemotherapy-induced premature ovarian insufficiency
por: Zhang, Shenghui, et al.
Publicado: (2023)

Neural stem cells, inflammation and NF-κB: basic principle of maintenance and repair or origin of brain tumours?
por: Widera, D, et al.
Publicado: (2008)

EZH2 Phosphorylation Promotes Self-Renewal of Glioma Stem-Like Cells Through NF-κB Methylation
por: Liu, Hailong, et al.
Publicado: (2019)

Recent Advances in Translational Adipose-Derived Stem Cell Biology
por: Widera, Darius
Publicado: (2021)

PFKFB3 Regulates Chemoresistance, Metastasis and Stemness via IAP Proteins and the NF-κB Signaling Pathway in Ovarian Cancer
por: Jiang, Yu-xin, et al.
Publicado: (2022)

Development and Characterisation of a Novel NF-κB Reporter Cell Line for Investigation of Neuroinflammation
por: Zeuner, Marie-Theres, et al.
Publicado: (2017)

Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer
por: Shaik Fakiruddin, Kamal, et al.
Publicado: (2019)

A Comparative Study of Non-Viral Gene Delivery Techniques to Human Adipose-Derived Mesenchymal Stem Cell
por: Halim, Nur Shuhaidatul Sarmiza Abdul, et al.
Publicado: (2014)

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma
por: Jayawant, Eleanor, et al.
Publicado: (2023)

Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons
por: Mikenberg, Ilja, et al.
Publicado: (2007)

Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour
por: Shaik Fakiruddin, Kamal, et al.
Publicado: (2018)

Suppression of EGFR/PKC-δ/NF-κB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer
por: Yueh, Po-Fu, et al.
Publicado: (2021)

Editorial: Characteristics and behaviors of hematopoietic stem cells and leukemia stem cells in hematologic malignancies
por: Zhang, Haojian, et al.
Publicado: (2022)

C1ql4 regulates breast cancer cell stemness and epithelial-mesenchymal transition through PI3K/AKT/NF-κB signaling pathway
por: Xu, Fan, et al.
Publicado: (2023)

Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells
por: Widera, Darius, et al.
Publicado: (2012)

The NF-κB Pathway and Cancer Stem Cells
por: Rinkenbaugh, Amanda L., et al.
Publicado: (2016)

Combination of Tanshinone IIA and Cisplatin Inhibits Esophageal Cancer by Downregulating NF-κB/COX-2/VEGF Pathway
por: Liao, Xiaozhong, et al.
Publicado: (2020)

Editorial: Repair and regenerative mechanisms by stem/progenitor cells and secretome: The golden twenties of translational medicine
por: Gramignoli, Roberto, et al.
Publicado: (2022)

G6PD-NF-κB-HGF Signal in Gastric Cancer-Associated Mesenchymal Stem Cells Promotes the Proliferation and Metastasis of Gastric Cancer Cells by Upregulating the Expression of HK2
por: Chen, Bin, et al.
Publicado: (2021)

Editorial: Tissue Repair and Regenerative Mechanisms by Stem/Progenitor Cells and Their Secretome
por: Gramignoli, Roberto, et al.
Publicado: (2019)

Mitochondrial Fission Factor (MFF) Inhibits Mitochondrial Metabolism and Reduces Breast Cancer Stem Cell (CSC) Activity
por: Sánchez-Alvarez, Rosa, et al.
Publicado: (2020)

Corrigendum: Combination of Tanshinone IIA and Cisplatin Inhibits Esophageal Cancer by Downregulating NF-κB/COX-2/VEGF Pathway
por: Liao, Xiaozhong, et al.
Publicado: (2021)

Identification of Biomarkers for Controlling Cancer Stem Cell Characteristics in Bladder Cancer by Network Analysis of Transcriptome Data Stemness Indices
por: Pan, Shen, et al.
Publicado: (2019)

EV-Mediated Chemoresistance in the Tumor Microenvironment: Is NF-κB a Player?
por: Di Vito Nolfi, Mauro, et al.
Publicado: (2022)

The Transcription Factor NF-κB in Stem Cells and Development
por: Kaltschmidt, Christian, et al.
Publicado: (2021)

Editorial: Current progress in mesenchymal stem/stromal cell research, volume II
por: da Silva Meirelles, Lindolfo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_60lflthbr30jkqfoj72h5njf47