Oncofertility in the setting of advanced cervical cancer - A case report

OBJECTIVE: To consider fertility options in women with advanced cervical cancer. DESIGN: Case report. SETTING: Large tertiary care center. PATIENT: A 30-year-old nulligravida woman diagnosed with FIGO Stage IB(I) squamous cell carcinoma of the cervix that had metastasized to a pelvic lymph node. INTERVENTIONS: Robotic radical trachelectomy with pelvic lymphadenectomy and cerclage placement, followed by ovarian stimulation with oocyte retrieval and in vitro fertilization. Subsequent therapy included adjuvant chemoradiation and embryo transfer to a surrogate mother. MAIN OUTCOME MEASURES: Cervical cancer remission, live birth from surrogate pregnancy. RESULTS: 33-year-old woman in her third year of remission from advanced cervical cancer with healthy twin girls. CONCLUSIONS: Fertility options may exist for patients even in the setting of metastatic cervical cancer. Early involvement of a reproductive endocrinologist is imperative. This case emphasizes the importance of cross-specialty communication.