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Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy

We report a case of a 26-year-old female patient treated with nivolumab for peritoneal implants from small-cell ovarian cancer. Pulmonary changes were depicted on follow-up examinations, namely, consolidations and scattered ground glass opacities, without any remarkable pulmonary complaints or labor...

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Detalles Bibliográficos
Autores principales: Ip, Joana, Beliao, Sara, Valente-Matos, Rogerio, Gil, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966623/
https://www.ncbi.nlm.nih.gov/pubmed/29849854
http://dx.doi.org/10.1016/j.radcr.2018.02.015
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author Ip, Joana
Beliao, Sara
Valente-Matos, Rogerio
Gil, Nuno
author_facet Ip, Joana
Beliao, Sara
Valente-Matos, Rogerio
Gil, Nuno
author_sort Ip, Joana
collection PubMed
description We report a case of a 26-year-old female patient treated with nivolumab for peritoneal implants from small-cell ovarian cancer. Pulmonary changes were depicted on follow-up examinations, namely, consolidations and scattered ground glass opacities, without any remarkable pulmonary complaints or laboratory changes. Both infectious and progressive diseases were ruled out. The condition was attributed to nivolumab side effect, and total remission was documented, followed by corticosteroids administration. We present clinical details and imaging findings, followed by a discussion where pulmonary toxicity can often be mistaken with infection or secondary involvement.
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spelling pubmed-59666232018-05-30 Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy Ip, Joana Beliao, Sara Valente-Matos, Rogerio Gil, Nuno Radiol Case Rep Oncology We report a case of a 26-year-old female patient treated with nivolumab for peritoneal implants from small-cell ovarian cancer. Pulmonary changes were depicted on follow-up examinations, namely, consolidations and scattered ground glass opacities, without any remarkable pulmonary complaints or laboratory changes. Both infectious and progressive diseases were ruled out. The condition was attributed to nivolumab side effect, and total remission was documented, followed by corticosteroids administration. We present clinical details and imaging findings, followed by a discussion where pulmonary toxicity can often be mistaken with infection or secondary involvement. Elsevier 2018-03-06 /pmc/articles/PMC5966623/ /pubmed/29849854 http://dx.doi.org/10.1016/j.radcr.2018.02.015 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Ip, Joana
Beliao, Sara
Valente-Matos, Rogerio
Gil, Nuno
Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
title Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
title_full Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
title_fullStr Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
title_full_unstemmed Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
title_short Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
title_sort pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966623/
https://www.ncbi.nlm.nih.gov/pubmed/29849854
http://dx.doi.org/10.1016/j.radcr.2018.02.015
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