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Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy
We report a case of a 26-year-old female patient treated with nivolumab for peritoneal implants from small-cell ovarian cancer. Pulmonary changes were depicted on follow-up examinations, namely, consolidations and scattered ground glass opacities, without any remarkable pulmonary complaints or labor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966623/ https://www.ncbi.nlm.nih.gov/pubmed/29849854 http://dx.doi.org/10.1016/j.radcr.2018.02.015 |
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author | Ip, Joana Beliao, Sara Valente-Matos, Rogerio Gil, Nuno |
author_facet | Ip, Joana Beliao, Sara Valente-Matos, Rogerio Gil, Nuno |
author_sort | Ip, Joana |
collection | PubMed |
description | We report a case of a 26-year-old female patient treated with nivolumab for peritoneal implants from small-cell ovarian cancer. Pulmonary changes were depicted on follow-up examinations, namely, consolidations and scattered ground glass opacities, without any remarkable pulmonary complaints or laboratory changes. Both infectious and progressive diseases were ruled out. The condition was attributed to nivolumab side effect, and total remission was documented, followed by corticosteroids administration. We present clinical details and imaging findings, followed by a discussion where pulmonary toxicity can often be mistaken with infection or secondary involvement. |
format | Online Article Text |
id | pubmed-5966623 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59666232018-05-30 Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy Ip, Joana Beliao, Sara Valente-Matos, Rogerio Gil, Nuno Radiol Case Rep Oncology We report a case of a 26-year-old female patient treated with nivolumab for peritoneal implants from small-cell ovarian cancer. Pulmonary changes were depicted on follow-up examinations, namely, consolidations and scattered ground glass opacities, without any remarkable pulmonary complaints or laboratory changes. Both infectious and progressive diseases were ruled out. The condition was attributed to nivolumab side effect, and total remission was documented, followed by corticosteroids administration. We present clinical details and imaging findings, followed by a discussion where pulmonary toxicity can often be mistaken with infection or secondary involvement. Elsevier 2018-03-06 /pmc/articles/PMC5966623/ /pubmed/29849854 http://dx.doi.org/10.1016/j.radcr.2018.02.015 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Ip, Joana Beliao, Sara Valente-Matos, Rogerio Gil, Nuno Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
title | Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
title_full | Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
title_fullStr | Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
title_full_unstemmed | Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
title_short | Pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
title_sort | pulmonary side effects of nivolumab in a patient treated for gynecological malignancy |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966623/ https://www.ncbi.nlm.nih.gov/pubmed/29849854 http://dx.doi.org/10.1016/j.radcr.2018.02.015 |
work_keys_str_mv | AT ipjoana pulmonarysideeffectsofnivolumabinapatienttreatedforgynecologicalmalignancy AT beliaosara pulmonarysideeffectsofnivolumabinapatienttreatedforgynecologicalmalignancy AT valentematosrogerio pulmonarysideeffectsofnivolumabinapatienttreatedforgynecologicalmalignancy AT gilnuno pulmonarysideeffectsofnivolumabinapatienttreatedforgynecologicalmalignancy |