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Toxicokinetics in Risk Evaluations
[Image: see text] Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen.
Autor principal: | |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966791/ https://www.ncbi.nlm.nih.gov/pubmed/29641185 http://dx.doi.org/10.1021/acs.chemrestox.8b00061 |
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author | Punt, Ans |
author_facet | Punt, Ans |
author_sort | Punt, Ans |
collection | PubMed |
description | [Image: see text] Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen. |
format | Online Article Text |
id | pubmed-5966791 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | American Chemical
Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-59667912018-05-25 Toxicokinetics in Risk Evaluations Punt, Ans Chem Res Toxicol [Image: see text] Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen. American Chemical Society 2018-04-11 2018-05-21 /pmc/articles/PMC5966791/ /pubmed/29641185 http://dx.doi.org/10.1021/acs.chemrestox.8b00061 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes. |
spellingShingle | Punt, Ans Toxicokinetics in Risk Evaluations |
title | Toxicokinetics
in Risk Evaluations |
title_full | Toxicokinetics
in Risk Evaluations |
title_fullStr | Toxicokinetics
in Risk Evaluations |
title_full_unstemmed | Toxicokinetics
in Risk Evaluations |
title_short | Toxicokinetics
in Risk Evaluations |
title_sort | toxicokinetics
in risk evaluations |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966791/ https://www.ncbi.nlm.nih.gov/pubmed/29641185 http://dx.doi.org/10.1021/acs.chemrestox.8b00061 |
work_keys_str_mv | AT puntans toxicokineticsinriskevaluations |