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Toxicokinetics in Risk Evaluations

[Image: see text] Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen.

Detalles Bibliográficos
Autor principal: Punt, Ans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966791/
https://www.ncbi.nlm.nih.gov/pubmed/29641185
http://dx.doi.org/10.1021/acs.chemrestox.8b00061
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author Punt, Ans
author_facet Punt, Ans
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description [Image: see text] Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen.
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spelling pubmed-59667912018-05-25 Toxicokinetics in Risk Evaluations Punt, Ans Chem Res Toxicol [Image: see text] Quantitative predictions of in vivo chemical levels based on in vitro data will become a cornerstone of next generation nonanimal risk evaluations. Both regulatory and scientific experience with quantitative toxicokinetics must increase now for this transition to happen. American Chemical Society 2018-04-11 2018-05-21 /pmc/articles/PMC5966791/ /pubmed/29641185 http://dx.doi.org/10.1021/acs.chemrestox.8b00061 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Punt, Ans
Toxicokinetics in Risk Evaluations
title Toxicokinetics in Risk Evaluations
title_full Toxicokinetics in Risk Evaluations
title_fullStr Toxicokinetics in Risk Evaluations
title_full_unstemmed Toxicokinetics in Risk Evaluations
title_short Toxicokinetics in Risk Evaluations
title_sort toxicokinetics in risk evaluations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966791/
https://www.ncbi.nlm.nih.gov/pubmed/29641185
http://dx.doi.org/10.1021/acs.chemrestox.8b00061
work_keys_str_mv AT puntans toxicokineticsinriskevaluations