Activation of β-catenin signaling in aggrecan-expressing cells in temporomandibular joint causes osteoarthritis-like defects

β-Catenin plays a critical role in cartilage formation and development. To further understand the role of β-catenin in osteoarthritis (OA) development in temporomandibular joint (TMJ), we have generated β-catenin conditional activation mice (β-cat(ex3)(Agc1CreER)) by breeding Agc1-CreER mice with β-...

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Detalles Bibliográficos
Autores principales: Hui, Tianqian, Zhou, Yachuan, Wang, Tingyu, Li, Jun, Zhang, Shanxing, Liao, Lifan, Gu, Jianhong, Ye, Ling, Zhao, Lan, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966811/
https://www.ncbi.nlm.nih.gov/pubmed/29686224
http://dx.doi.org/10.1038/s41368-018-0016-z

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