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Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss
Hypoxia (low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation of hypoxia-inducible factor 1 (HIF-1). Hypoxia interferes degradation of HIF-1 alph...
Autores principales: | Hirai, Kimito, Furusho, Hisako, Hirota, Kiichi, Sasaki, Hajime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966812/ https://www.ncbi.nlm.nih.gov/pubmed/29654284 http://dx.doi.org/10.1038/s41368-018-0015-0 |
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