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Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss

Hypoxia (low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation of hypoxia-inducible factor 1 (HIF-1). Hypoxia interferes degradation of HIF-1 alph...

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Detalles Bibliográficos
Autores principales: Hirai, Kimito, Furusho, Hisako, Hirota, Kiichi, Sasaki, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966812/
https://www.ncbi.nlm.nih.gov/pubmed/29654284
http://dx.doi.org/10.1038/s41368-018-0015-0

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