Novel insights into neuroinflammation: bacterial lipopolysaccharide, tumor necrosis factor α, and Ureaplasma species differentially modulate atypical chemokine receptor 3 responses in human brain microvascular endothelial cells

BACKGROUND: Atypical chemokine receptor 3 (ACKR3, synonym CXCR7) is increasingly considered relevant in neuroinflammatory conditions, in which its upregulation contributes to compromised endothelial barrier function and may ultimately allow inflammatory brain injury. While an impact of ACKR3 has bee...

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Detalles Bibliográficos
Autores principales: Silwedel, Christine, Speer, Christian P., Haarmann, Axel, Fehrholz, Markus, Claus, Heike, Buttmann, Mathias, Glaser, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966865/
https://www.ncbi.nlm.nih.gov/pubmed/29792190
http://dx.doi.org/10.1186/s12974-018-1170-0

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