Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer

BACKGROUND: Reduced expression of retinoic acid-induced 2 (RAI2) was found in breast cancer. The regulation and function of RAI2 in human colorectal cancer (CRC) remain unclear. METHODS: Eight CRC cell lines and 237 cases of primary CRC were analyzed. Methylation-specific PCR (MSP), flow cytometry,...

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Detalles Bibliográficos
Autores principales: Yan, Wenji, Wu, Kongming, Herman, James G., Xu, Xiuduan, Yang, Yunsheng, Dai, Guanghai, Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966878/
https://www.ncbi.nlm.nih.gov/pubmed/29796120
http://dx.doi.org/10.1186/s13148-018-0501-4

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