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Involvement of the CB(2) cannabinoid receptor in cell growth inhibition and G0/G1 cell cycle arrest via the cannabinoid agonist WIN 55,212–2 in renal cell carcinoma
BACKGROUND: The anti-tumor properties of cannabinoids have been investigated in many in vitro and in vivo studies. Many of these anti-tumor effects are mediated via cannabinoid receptor types 1 and 2 (CB(1) and CB(2)), comprising the endocannabinoid system (ECS). In this study, we investigated the E...
Autores principales: | Khan, Mohammed I., Sobocińska, Anna A., Brodaczewska, Klaudia K., Zielniok, Katarzyna, Gajewska, Malgorzata, Kieda, Claudine, Czarnecka, Anna M., Szczylik, Cezary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966919/ https://www.ncbi.nlm.nih.gov/pubmed/29792186 http://dx.doi.org/10.1186/s12885-018-4496-1 |
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