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Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma

BACKGROUND: Asthma is a chronic respiratory condition, with airway hyperresponsiveness (AHR) and inflammation as hallmarks. The hypothesis that the substantially increased expression of arginase 1 in activated macrophages limits the availability of L-arginine for nitric oxide synthesis, and thus inc...

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Detalles Bibliográficos
Autores principales:	Cloots, Roy H. E., Poynter, Matthew E., Terwindt, Els, Lamers, Wouter H., Köhler, S. Eleonore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967058/ https://www.ncbi.nlm.nih.gov/pubmed/29792217 http://dx.doi.org/10.1186/s12931-018-0809-9

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